Dr. De Franco obtained a B.A. degree in biochemistry from the University of Pennsylvania, a D.M.D. degree from the University of Connecticut and the certificate in Orthodontics with a Doctorate of Medical Sciences degree in Oral Biology from Harvard University. He moved to Milan in 1992 where he has been working ever since in private practice limited to orthodontics. He is a Diplomate of the Orthodontic Boards ABO, EBO and IBO. He has served as Chairman of Examiners and President of the European Board of Orthodontics. He is a member of the AAO, EOS, Harvard Society for the Advancement of Orthodontics and is an active member of SIDO, Italian Academy of Orthodontics, as well as the European Academy of Esthetic Dentistry and the Eastern Component of the Angle Society. He was President of the Angle Society in 2017-2018 and President of the Italian Academy of Orthodontics in 2021. He has numerous publications and is a reviewer for several orthodontic journals.